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Updated: Apr 11, 2026

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
Published on: June 13, 2025
Sleep duration and sleep disorder with red blood cell distribution width
1Department of Health, Exercise Science and Recreation Management, University of Mississippi, University, MS, USA. pdloprin@olemiss.edu.
Both insufficient and excessive sleep duration, along with diagnosed sleep disorders, are linked to higher red blood cell distribution width (RDW) levels in adults. This suggests sleep quality impacts hematological markers.
Area of Science:
- Hematology
- Sleep Medicine
- Public Health
Background:
- Red blood cell distribution width (RDW) is a measure of the variation in red blood cell size.
- RDW is increasingly recognized as a potential indicator of various health conditions.
- Sleep is crucial for overall health and well-being.
Purpose of the Study:
- To investigate the relationship between sleep duration and sleep disorders with RDW levels.
- To determine if abnormal sleep patterns are associated with elevated RDW.
Main Methods:
- Utilized data from 17,621 adults from the National Health and Nutrition Examination Survey (2005-2012).
- Assessed sleep duration and diagnosed sleep disorders via questionnaire.
- Measured RDW from blood samples.
Main Results:
- Sleeping 5, 9, or ≥10 hours per night was associated with increased odds of elevated RDW compared to 7-8 hours.
- Individuals with physician-diagnosed sleep disorders exhibited higher RDW values.
- Statistical significance was observed for these associations (p < .05).
Conclusions:
- Sleep duration and the presence of sleep disorders are significantly associated with elevated RDW.
- These findings highlight the potential impact of sleep on hematological parameters like RDW.
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