Prostate-Specific Membrane Antigen PET/CT in Splenic Sarcoidosis
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Published on: January 22, 2018
Carsten Kobe1, David Maintz, Thomas Fischer
1From the Departments of *Nuclear Medicine and †Radiology, University Hospital of Cologne, Cologne, Germany.
Abstract:
A 65-year-old man who had prostate cancer presented with slightly progressive prostate-specific antigen values. In this situation of biochemical relapse, prostate-specific membrane antigen (PSMA) PET/CT has proven to be superior to choline PET. The Ga-PSMA PET/CT of our patient revealed PSMA-positive tissue in the spleen. Although the localization was not typical for metastases, metastasis could not be excluded because of the intense focal tracer uptake. A supplementary MRI was performed but also failed to rule out a malignant origin. Finally, biopsy confirmed benign disease in the spleen in the form of granulomatous disease.
