[Primary myxedema in an adult. Notes on a case]

In the case of adult primary myxedema reported the diagnostic suspicion aroused by objective examination was confirmed by assaying the hypophysial-thyroid hormones (blood T4 and T3 below normal levels) and by the behaviour of certain muscle enzymes (CPK, LDH, GOT) that bore witness to diffuse muscle and bone damage (hypothyroid "myopathy"). The presence of antithyroid antibodies, though in small amounts suggested earlier and unnoticed thyroiditis as a possible aetiopathogenic explanation. The clinical and metabolic picture undoubtedly benefited from treatment with L-Thyroxine.