Related Experiment Video
Updated: Apr 11, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
A cardiorenal-pulmonary-cutaneous-muscle syndrome
Sebastian Schöpp1, Saban Elitok1, Markus Bieringer1
1Franz-Volhard Clinic , HELIOS Klinikum-Berlin , Berlin , Germany.
Abstract:
Anti-synthetase syndrome is a relatively recently described auto-immune disease characterized by auto-antibodies to enzymes that acetylate transfer RNA (tRNA). Interstitial pulmonary disease and inflammatory myopathy are regular findings. Our patient also exhibited a lupus-like glomerulonephritis. An important clue was the presence of 'mechanics' hands. Nephrologists need to be aware of this syndrome.
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