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About the Therapy of Laryngotracheitis (Croup): Significance of Rectal Dosage Forms
Eckhard Beubler1, Peter Dittrich
1Institute of Experimental and Clinical Pharmacology, Medical University Graz, Graz, Austria.
Abstract:
Glucocorticoids are drugs of choice for treatment of laryngotracheitis (croup). They may be administered orally as tablets or juice, locally as inhalation or rectally as suppository or capsule. If doctors decide to use a rectal administration for practical reasons, it is obvious from a pharmacokinetic and pharmacodynamic point of view that prednisolone capsules have an earlier and stronger anti-inflammatory effect than a prednisone suppository.
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