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Postradiation dermatofibrosarcoma protuberans : case report and literature review
1Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Acta Chirurgica Belgica
|May 30, 2015
Summary
This study reports the first case of postradiation dermatofibrosarcoma protuberans (DFSP) in an Asian patient, developing on a chest wall scar after radiotherapy. The patient achieved a good outcome with radical surgical excision and flap reconstruction, showing no recurrence after 12 months.
Area of Science:
- Oncology
- Dermatology
- Surgical Oncology
Background:
- Radiotherapy is a known risk factor for secondary soft tissue sarcomas.
- Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous malignancy.
- Postradiation DFSP is exceptionally rare, with limited documented cases.
Observation:
- A case of DFSP developed on an irradiated scar in an Asian woman.
- The lesion was located on the right chest wall, a site previously treated with radiotherapy.
- Immunohistochemistry confirmed the diagnosis of DFSP.
Findings:
- This is the first reported case of postradiation DFSP in an Asian individual.
- Radical surgical excision and latissimus dorsi island myocutaneous flap reconstruction were performed.
- The patient demonstrated a favorable outcome with no signs of recurrence at 12 months post-surgery.
Implications:
- Highlights the potential for DFSP development following radiotherapy, even in previously unreported ethnic groups.
- Emphasizes the importance of long-term surveillance for patients with a history of radiation therapy.
- Demonstrates the efficacy of surgical management, including flap reconstruction, for postradiation DFSP.
