Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperammonaemic coma in ureterosigmoid urinary diversion.

R M Oliver1, S Talbot, G V Raman

  • 1Department of Renal Medicine, University of Southampton, St Mary's Hospital, Portsmouth, UK.

Postgraduate Medical Journal
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combined spinal epidural anaesthesia for caesarean delivery of quadruplets: a case report.

International journal of obstetric anesthesia·2025
Same author

Profiling of how nociceptor neurons detect danger - new and old foes.

Journal of internal medicine·2019
Same author

Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same author

Elevated nocturnal desaturation index predicts mortality in interstitial lung disease.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG·2013
Same author

Brain kinin B₁ receptor contributes to the onset of stereotypic nocifensive behavior in rat.

Behavioural brain research·2012
Same author

Predicting future pollution exceedances under emission controls.

Environmental science & technology·2012
Same journal

Dapagliflozin-induced anaphylactic shock.

Postgraduate medical journal·2026
Same journal

Comparative efficacy of Janus kinase inhibitors in severe alopecia areata: a network meta-analysis based on randomized controlled trials.

Postgraduate medical journal·2026
Same journal

Two cases of toxic epidermal necrolysis with severe ocular involvement treated with adjunctive tofacitinib.

Postgraduate medical journal·2026
Same journal

Diastolic dysfunction and diabetes: the DIADAD study-a retrospective cohort study from Liverpool.

Postgraduate medical journal·2026
Same journal

Care, cash, and proof: forensic accountability for war-related starvation.

Postgraduate medical journal·2026
Same journal

Response to traumatic injuries in polo players in England.

Postgraduate medical journal·2026
See all related articles

A patient with ureterosigmoid anastomosis experienced confusion and coma due to hyperammonaemia. Treatment with sodium benzoate and sodium phenylacetate, alongside a protein-restricted diet, successfully managed ammonia levels.

Area of Science:

  • Nephrology
  • Neurology
  • Metabolic Disorders

Background:

  • Ureterosigmoid anastomosis is a surgical procedure connecting the ureters to the sigmoid colon.
  • This procedure can lead to metabolic complications, including hyperammonaemia.

Observation:

  • A patient with a history of ureterosigmoid anastomosis presented with recurrent confusion, agitation, and aggressive behavior.
  • These neurological symptoms progressed to coma, indicating a severe underlying condition.

Findings:

  • Investigations revealed profound hyperammonaemia (elevated ammonia levels in the blood).
  • The patient's condition improved significantly with medical management, including sodium benzoate and sodium phenylacetate.
  • A possible urinary tract infection was considered a contributing factor, but no definitive cause was identified.

Related Experiment Videos

Implications:

  • This case highlights the potential for severe neurological complications in patients with ureterosigmoid anastomosis.
  • Prompt recognition and management of hyperammonaemia are crucial for patient recovery.
  • Long-term management may involve dietary modifications, such as protein restriction, and continued monitoring of ammonia levels.