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The Relationship between Spontaneous Multi-Vessel Coronary Artery Dissection and Celiac Disease
Nermin Bayar1, Göksel Çağırcı1, Çağın Mustafa Üreyen1
1Department of Cardiology, Antalya Education and Research Hospital, Antalya, Turkey.
Insights
Celiac disease (CD) is linked to heart issues. This case report details a young male with CD experiencing spontaneous multi-vessel coronary artery dissection, a rare cardiac event.
Area of Science:
- Cardiology
- Gastroenterology
- Immunology
Background:
- Celiac disease (CD) is an immune-mediated enteropathy affecting the small intestine.
- Individuals with CD have a higher prevalence of cardiovascular conditions like coronary artery disease and atherosclerosis.
- The link between CD and cardiac events, particularly spontaneous coronary artery dissection (SCAD), requires further investigation.
Purpose of the Study:
- To report a rare case of spontaneous multi-vessel coronary artery dissection in a young male patient with celiac disease.
- To highlight the potential association between celiac disease and severe cardiovascular events.
Main Methods:
- Case report presentation.
- Review of patient's medical history, diagnostic findings, and clinical course.
Main Results:
- A young male patient with diagnosed celiac disease presented with acute myocardial infarction.
- Coronary angiography revealed spontaneous dissection in two major coronary arteries.
- This represents the first reported instance of spontaneous multi-vessel coronary artery dissection in a patient with celiac disease.
Conclusions:
- Celiac disease may be associated with an increased risk of spontaneous coronary artery dissection.
- This case underscores the importance of considering cardiovascular complications in patients with celiac disease.
- Further research is warranted to elucidate the pathophysiological mechanisms linking CD and SCAD.
Abstract:
Celiac disease (CD) is an immune-mediated enteropathy involving the small intestines. Genetic and environmental risk factors as well as autoimmunity have been linked to its etiology. Studies have shown that coronary artery disease, autoimmune myocarditis, arrhythmias and premature atherosclerosis are more prevalent in individuals with CD compared to individuals without the disease. In this case report a young male patient with CD presented with acute myocardial infarction with spontaneous coronary artery dissections of two vessels. To the best of our knowledge, this is the first case report of spontaneous multi-vessel coronary artery dissection in a patient with CD.
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