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Congenital pyloric atresia and associated anomalies: a case series

Rahul Gupta1, Varsha Soni1, Praveen Mathur1

  • 1Department of Paediatric Surgery, SPMCHI, SMS Medical College, Jaipur, India.

Journal of Neonatal Surgery
|May 30, 2015
PubMed

Insights

Congenital pyloric atresia (CPA) is a rare surgical condition. This study found an 81.8% survival rate in eleven patients, with sepsis being the cause of mortality in two cases.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Medical Genetics

Background:

  • Congenital pyloric atresia (CPA) is an extremely rare congenital anomaly of the gastric outlet.
  • It presents a significant surgical challenge due to its rarity and potential for associated anomalies.

Purpose of the Study:

  • To retrospectively analyze the clinical presentation, management, and outcomes of patients diagnosed with congenital pyloric atresia.
  • To identify associated anomalies and evaluate the effectiveness of different surgical interventions.

Main Methods:

  • Retrospective case series of eleven patients with CPA.
  • Data collected included age at diagnosis, sex, symptoms, associated anomalies, operative findings, surgical procedures, and patient outcomes.
  • Review of surgical records and patient charts.

Main Results:

  • Eleven patients (8 male: 3 female) were studied, with diagnosis ranging from 1 day to 3 years.
  • Associated anomalies were present in 36.6% of cases, including epidermolysis bullosa, esophageal atresia, and colonic atresia.
  • Type 1 CPA was most common (54.5%), followed by Type 2 (36.3%) and Type 3 (9%).
  • Surgical procedures included Heineke-Mickulicz pyloroplasty, Finney's pyloroplasty, and gastro-duodenostomy.
  • An overall survival rate of 81.8% was achieved, with two deaths attributed to sepsis.

Conclusions:

  • Congenital pyloric atresia requires prompt surgical intervention.
  • Associated anomalies are common and impact management and prognosis.
  • While surgical outcomes can be favorable, sepsis remains a significant risk factor for mortality.

Keywords:
Epidermolysis bullosaHeineke–Mickulicz pyloroplastyPyloric atresiapyloric diaphragm

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