Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electroconvulsive Therapy01:30

Electroconvulsive Therapy

2.2K
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
2.2K
Formation of the Platelet Plug01:22

Formation of the Platelet Plug

10.9K
The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
10.9K
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

10.4K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
10.4K
Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

1.9K
Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
1.9K
Introduction to Hemostasis01:05

Introduction to Hemostasis

17.9K
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
17.9K
Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

15.7K
Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
15.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting Warburg effect in Chinese hamster ovary cell culture with pyruvate dehydrogenase kinase inhibitors.

Biotechnology progress·2026
Same author

Evaluating the clinico-pathological features including the immunohistochemical and molecular landscape of synovial sarcoma cases from a tertiary care cancer referral centre in India.

BMC cancer·2025
Same author

Neuroendocrine carcinoma of the gall bladder: A clinicopathological report of 56 Cases from a tertiary care cancer center in North India.

Journal of cancer research and therapeutics·2025
Same author

Poorly Differentiated Aggressive Sacral Chordoma With Upfront Lung Metastases in a Child-A Case Report.

Clinical case reports·2025
Same author

ALK-positive large B-cell lymphoma: A study of six cases from an oncopathology center in North India.

Indian journal of pathology & microbiology·2025
Same author

Clinicopathological Significance and Prognostic Role of Her2neu Protein Expression in Patients with Carcinoma Stomach: A Prospective Study from Northern India.

South Asian journal of cancer·2023

Related Experiment Video

Updated: Apr 11, 2026

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
09:42

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

3.7K

Post electric shock reactive thrombocytosis.

Richa Katiyar1, Shashikant C U Patne2, Pranjal Pankaj3

  • 1Service Senior Resident, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University , Varanasi, Uttar Pradesh, India .

Journal of Clinical and Diagnostic Research : JCDR
|May 30, 2015
PubMed
Summary
This summary is machine-generated.

Electric shock can cause significant thrombocytosis (high platelet count). This case report details a patient who developed marked thrombocytosis after an electric shock, which resolved with treatment.

Keywords:
Fluid therapyNeuropathyPlateletsTissue injury

More Related Videos

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.7K
Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.8K

Related Experiment Videos

Last Updated: Apr 11, 2026

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
09:42

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

3.7K
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.7K
Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.8K

Area of Science:

  • Internal Medicine
  • Hematology
  • Toxicology

Background:

  • Thrombocytosis is defined as a platelet count exceeding 400×10(9)/L.
  • Electric shock is a potential cause of tissue injury and subsequent thrombocytosis.

Observation:

  • A 45-year-old woman presented with neurological symptoms including weakness, tingling, and numbness in her lower limbs.
  • She had a history of electric shock exposure 15 days prior to admission.
  • Laboratory results showed a markedly elevated platelet count (1,570×10(9)/L), elevated serum uric acid, and mild increases in serum potassium and alanine transaminase.

Findings:

  • The patient's symptoms and neurological deficits resolved following hospitalization and treatment.
  • Her platelet count significantly declined with medical intervention.
  • This case highlights a rare instance of marked thrombocytosis secondary to electric shock.

Implications:

  • Electric shock should be considered as a potential trigger for thrombocytosis in clinical evaluations.
  • Further research into the pathophysiology linking electric shock and thrombocytosis is warranted.
  • Understanding this association can improve diagnostic and treatment strategies for patients with similar presentations.