Related Experiment Video

Updated: Apr 11, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
09:35

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

985

Relationship between intracerebral hemorrhage and diabetes mellitus: a case-control study

Omid Hesami1, Hosein Delavar Kasmaei2, Fateme Matini2

  • 1Faculty, Department of Neurology, Imam Hosein Hospital, Shahid Beheshti University of Medical Sciences , Tehran, Iran .

Journal of Clinical and Diagnostic Research : JCDR
|May 30, 2015
PubMed

Insights

Diabetes mellitus was not significantly linked to intracerebral hemorrhage (ICH) overall. However, a higher prevalence was observed in younger patients, suggesting a potential association requiring further investigation.

Area of Science:

  • Neurology
  • Endocrinology
  • Epidemiology

Background:

  • The link between diabetes mellitus and intracerebral hemorrhage (ICH) remains debated.
  • Comorbidities like diabetes mellitus may elevate ICH risk.
  • This study investigates the association between diabetes mellitus and ICH occurrence.

Purpose of the Study:

  • To assess the role of diabetes mellitus in the development of intracerebral hemorrhage.
  • To determine if diabetes mellitus is a risk factor for ICH.

Main Methods:

  • A case-control study was conducted with 120 ICH patients and 135 controls (low back pain).
  • Diabetes mellitus prevalence was compared between groups.
  • Statistical analysis included t-tests and chi-square/Fisher's exact tests.

Main Results:

  • No significant overall difference in diabetes mellitus prevalence between ICH patients (33.1%) and controls (22.2%) (p=0.054).
  • A significant association was found in patients younger than 60 years (27.8% vs. 7.4%, p=0.042).
  • Diabetes mellitus was not linked to bleeding in specific brain areas.

Conclusions:

  • No significant association between diabetes mellitus and intracerebral hemorrhage was found in the general study population.
  • A notable exception was observed in patients under 60 years old.
  • Further research is needed to clarify the correlation between diabetes mellitus and ICH in this population.
Abstract

Keywords:
HemorrhageHypertensionStroke

More Related Videos

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model08:18

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

Published on: February 8, 2022

3.2K
Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.3K

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.3K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.5K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.8K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.9K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
646