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Increased locomotor activity of rats by self-stimulation in a running wheel
H Schwarzberg1, N Roth, I Stürmer
1Institute of Physiology, Medical Academy, Magdeburg, G.D.R.
Physiology & Behavior
|October 1, 1989
Abstract:
A method was developed in which the intracranial self-stimulation of rats was dependent on their locomotor activity. During each rotation of a running wheel (= 0.75 m), six stimulus trains were administered via electrodes in the medial forebrain bundle. Under these conditions, animals increased their locomotor activity 112-fold, compared to a control condition without self-stimulation. This method may be a valuable procedure in various research fields where extreme increases in motor activity of laboratory animals are advantageous.