Mechanics of lipid bilayers: What do we learn from pore-spanning membranes?

The mechanical properties of biological membranes have become increasingly important not only from a biophysical viewpoint but also as they play a substantial role in the information transfer in cells and tissues. This minireview summarizes some of our recent understanding of the mechanical properties of artificial model membranes with particular emphasis on membranes suspending an array of pores, so called pore-spanning membranes. A theoretical description of the mechanical properties of these membranes might pave the way to biophysically describe and understand the complex behavior of native biological membranes. This article is part of a Special Issue entitled: Mechanobiology.