Related Experiment Video
Updated: Apr 11, 2026

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
Published on: November 1, 2014
Strangles in horses can be caused by vaccination with Pinnacle I. N
Ray Cursons1, Olivia Patty1, Karen F Steward2
1School of Science, University of Waikato, Hamilton, New Zealand.
Abstract:
The differentiation of live attenuated vaccine strains from their progenitor and wild-type counterparts is important for ongoing surveillance of product safety and improved guidelines on their use. We utilised a genome sequencing approach to confirm that two cases of strangles in previously healthy horses that had received the Pinnacle I. N. vaccine (Zoetis) were caused by the vaccine strain. Our data shed new light on the safety of this vaccine and suggest that factors beyond the maturity of the animal's immune system influence the development of adverse reactions.
Related Concept Videos
Diphtheria
Rheumatic Heart Disease I: Introduction
Atypical Pneumonia
Vaccinations
Bacterial Phylum Spirochaetes
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:

