Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarker screen-guided care for preterm birth risk in nulliparous pregnancies: a subgroup analysis of the PRIME randomized controlled trial.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2026
Same author

The association of maternal body mass index and cesarean delivery after preterm induction of labor.

American journal of obstetrics & gynecology MFM·2026
Same author

Hospital-Level Variation in Antenatal Corticosteroids for Late Preterm Births.

medRxiv : the preprint server for health sciences·2026
Same author

The Influence of Hindsight and Outcome Bias on Fetal Heart Rate Interpretation and Judgments of Obstetric Care Quality.

American journal of perinatology·2026
Same author

Disparities in low dose aspirin use for preeclampsia risk reduction and opportunities for improvement.

Seminars in perinatology·2026
Same author

Antenatal Steroid Exposure among Late Preterm Births Following Updated Clinical Guidance.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Apr 11, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy
05:52

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

Published on: October 28, 2022

1.1K

Does magnesium exposure affect neonatal resuscitation?

Daphnie Drassinower1, Alexander M Friedman1, Heather Levin1

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY.

American Journal of Obstetrics and Gynecology
|June 1, 2015
PubMed
Summary
This summary is machine-generated.

Maternal magnesium sulfate exposure at delivery did not increase the risk of adverse neonatal resuscitation outcomes. This finding is crucial for neonatal care planning and patient counseling regarding magnesium use during pregnancy.

Keywords:
immediate neonatal resuscitationmagnesium sulfateneonatal outcomeneuroprotection

More Related Videos

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.4K
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.5K

Related Experiment Videos

Last Updated: Apr 11, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy
05:52

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

Published on: October 28, 2022

1.1K
The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.4K
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.5K

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Pharmacology

Background:

  • Maternal magnesium exposure during labor has been debated for potential adverse neonatal effects.
  • Previous studies show conflicting evidence regarding magnesium's impact on neonatal resuscitation outcomes.
  • Clarifying these effects is essential for informed clinical practice.

Purpose of the Study:

  • To investigate the association between maternal magnesium exposure at delivery and neonatal resuscitation.
  • To determine if magnesium administration impacts composite adverse neonatal resuscitation outcomes.
  • To analyze short-term neonatal outcomes following magnesium exposure.

Main Methods:

  • Secondary analysis of a randomized controlled trial on magnesium sulfate for cerebral palsy prevention.
  • Evaluation of a composite adverse neonatal resuscitation outcome (5-minute Apgar <7, oxygen use, intubation, chest compressions, hypotension, hypotonicity).
  • Subgroup analysis for deliveries at ≥30 weeks gestation; log-linear regression used for confounder control.

Main Results:

  • Analysis included 1047 neonates; 461 (44%) were exposed to magnesium.
  • No increased risk for the primary composite adverse neonatal resuscitation outcome was observed with magnesium exposure.
  • Individual adverse neonatal outcomes and other short-term outcomes showed no association with magnesium exposure.

Conclusions:

  • Maternal magnesium sulfate exposure at delivery does not adversely affect neonatal resuscitation.
  • Neonatal short-term outcomes are not negatively impacted by magnesium exposure.
  • Findings support current clinical guidelines and aid in patient counseling regarding magnesium use.