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EHDA Spraying: A Multi-Material Nano-Engineering Route.

Rita Haj-Ahmad, Manoochehr Rasekh, Kazem Nazari

  • 1State Key Labortory of Silcon Materials, School of Materials Science and Engineering, Zhejiang University, Hangzhou, P.R.China 310027. xiang.li@zju.edu.cn.

Current Pharmaceutical Design
|June 2, 2015
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Electrohydrodynamic atomization (EHDA) is a key technology for creating nanoparticles. This review highlights electrospraying (ESy) developments for healthcare applications using metals, polymers, and ceramics.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Electrohydrodynamic atomization (EHDA) has emerged as a significant platform technology over the last two decades.
  • EHDA enables the fabrication of nano- and micro-scaled structures with controlled surface and encapsulation features.
  • Key EHDA techniques include electrospraying (ESy) and electrospinning (ESp), with ESy being crucial for particle generation.

Purpose of the Study:

  • To review key developments in electrospraying (ESy) within nanotechnologies.
  • To focus on ESy applications in healthcare, particularly using metals, polymers, and ceramics.
  • To provide insights into particle formation, process parameters, and material specifications in ESy.

Main Methods:

  • Review of existing literature on EHDA and ESy.

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  • Analysis of particle formation mechanisms during ESy.
  • Evaluation of process parameters and material requirements for ESy.

    • Main Results:

    • ESy is a vital process for fabricating nano- and micro-particles.
    • EHDA allows for the creation of engineered therapies using diverse materials like metals, polymers, ceramics, peptides, DNA, and cells.
    • Control over surface and encapsulation features is achievable in a single step.

    Conclusions:

    • Electrospraying (ESy) is a critical nanotechnology for healthcare applications.
    • Further research into ESy processes, parameters, and materials is vital for advancing engineered therapies.
    • EHDA-derived nanostructures hold significant promise for emerging biomedical and healthcare research.