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Updated: Apr 11, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
Published on: February 7, 2021
Advances in Hyaluronic Acid-Based Drug Delivery Systems
Yan Jiao, Xin Pang, Guangxi Zhai1
1Department of Pharmaceutics College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China. professorgxzhai@126.com.
Abstract:
Hyaluronic acid (HA) is a relatively new polymer for the construction of drug delivery systems. CD44 and the receptor for HA-mediated motility play a key role in vivo for the receptor-mediated endocytosis of HA. Cellular uptake and the efficiency of tumor-targeted drug delivery are supposed to increase through utilizing HA as drug carriers. Currently, HA has provided a promising platform to physically encapsulate or chemically conjugate with various drugs. In this review, we presented the most latest advances in HA-based drug delivery systems and some forward-looking ideas are discussed.
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