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Electromechanical Assessment of Optogenetically Modulated Cardiomyocyte Activity
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Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology.

Laura Sartiani1, Maria Novella Romanelli, Alessandro Mugelli

  • 1Department of NeuroFarBa, C.I.M.M.B.A., University of Florence, Viale Pieraccini, 6, 50139 Florence, Italy. laura.sartiani@unifi.it.

Current Drug Targets
|June 2, 2015
PubMed
Summary

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are crucial for heart rhythm. Dysfunction in these cardiac channels can cause arrhythmias, but blockade with ivabradine shows therapeutic potential.

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