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Associations of maternal urinary perchlorate, thiocyanate, and nitrate with maternal thyroid function during pregnancy: Modification by iodine status in the MARBLES study.

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Thyroid disorders during pregnancy and postpartum.

Elizabeth N Pearce1

  • 1Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, MA, USA.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|June 2, 2015
PubMed
Summary
This summary is machine-generated.

Managing thyroid disease during pregnancy requires understanding physiological changes and potential impacts on both mother and child. This review covers current strategies and identifies areas needing further research for better outcomes.

Keywords:
Graves' diseasehypothyroidismpostpartum thyroid diseasepregnancythyrotoxicosis

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Area of Science:

  • Endocrinology
  • Obstetrics
  • Reproductive Health

Background:

  • Thyroid physiology undergoes significant changes during pregnancy.
  • Uncontrolled thyroid disease can negatively affect pregnancy and infant outcomes.
  • Effective management of maternal thyroid disorders is crucial.

Purpose of the Study:

  • To review current strategies for managing thyroid disease in pregnant and postpartum individuals.
  • To highlight areas of ongoing debate and lack of consensus in thyroid disease management during pregnancy.

Main Methods:

  • Literature review of studies on thyroid disease in pregnancy.
  • Synthesis of evidence-based management guidelines.
  • Identification of consensus and controversial areas.

Main Results:

  • Gestational thyroid changes necessitate tailored management approaches.
  • Hypothyroidism and hyperthyroidism require careful monitoring and treatment during pregnancy.
  • Postpartum thyroid management is also addressed.

Conclusions:

  • Awareness of gestational thyroid adaptations is key for successful management.
  • Standardized guidelines are needed for areas lacking consensus.
  • Further research is recommended to optimize maternal and infant outcomes.