Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

1.9K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.9K
Behaviorism01:28

Behaviorism

8.1K
The field of behaviorism was pioneered by figures such as Ivan Pavlov, John B. Watson, and B.F. Skinner fundamentally shifted the focus of psychology to the observable and controllable aspects of human and animal behavior. This shift marked a critical evolution in the discipline, emphasizing scientific rigor and experimental methodology.
The core premise of behaviorism is its focus on observable behavior rather than internal thoughts or feelings. This approach argues that true scientific...
8.1K
Instinctive Drift01:05

Instinctive Drift

1.3K
Instinctive drift refers to the tendency of animals to revert to their innate behaviors despite repeated reinforcement. Breland and Breland demonstrated this concept in an experiment with a raccoon. The raccoon was trained to pick up two coins and place them in a container in exchange for food. Initially, the raccoon learned to associate the coins with food, making them a conditioned stimulus or a substitute for food. However, over time, the raccoon became less willing to put the coins into the...
1.3K
Associative Learning01:27

Associative Learning

2.0K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
2.0K
Real-World Application of Classical Conditioning01:15

Real-World Application of Classical Conditioning

2.4K
Classical conditioning not only includes the initial pairing of stimuli but also extends to more complex forms, such as higher-order conditioning. Higher-order conditioning involves creating associations beyond the primary conditioned stimulus, resulting in a chain of conditioned responses.
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Striatal pathways dissociably control action counting and goal-directed steering.

Nature neuroscience·2026
Same author

A dual-color miniature endoscope for calcium imaging in behaving mice.

iScience·2026
Same author

Basal ganglia output dynamically controls skilled forelimb kinematics in real time.

bioRxiv : the preprint server for biology·2026
Same author

A dual-color miniature endoscope for calcium imaging in behaving mice.

bioRxiv : the preprint server for biology·2026
Same author

The parafascicular nucleus of the thalamus orchestrates coordinated skeletomotor, autonomic, and aversive state transitions.

bioRxiv : the preprint server for biology·2026
Same author

Elucidating an anterior cingulate circuit for self-initiated actions and rescue of Parkinsonian akinesia.

bioRxiv : the preprint server for biology·2026
Same journal

Integrative perspectives on electroacupuncture modulation of vagal-cholinergic and neuro-immune-metabolic regulation in long COVID.

Frontiers in integrative neuroscience·2026
Same journal

Fatigue relief is possible.

Frontiers in integrative neuroscience·2026
Same journal

Progress and ongoing conceptual challenges "on the way to integrative human neuroscience"-ten years after.

Frontiers in integrative neuroscience·2026
Same journal

Consciousness emerges from temporal integration across biological scales: from cellular memory to phenomenological experience.

Frontiers in integrative neuroscience·2026
Same journal

High serum uric acid levels explains the negative impact of the altitude adaptation index on the brain electroencephalographic Microstate D under high-altitude hypoxic conditions.

Frontiers in integrative neuroscience·2026
Same journal

Synergistic efficacy of combined neurolysis and methylcobalamin in peripheral nerve injury: a randomized clinical trial.

Frontiers in integrative neuroscience·2026
See all related articles

Related Experiment Video

Updated: Apr 11, 2026

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
08:07

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats

Published on: August 24, 2016

9.7K

Elevated dopamine alters consummatory pattern generation and increases behavioral variability during learning.

Mark A Rossi1, Henry H Yin2

  • 1Department of Psychology and Neuroscience, Duke University Durham, NC, USA.

Frontiers in Integrative Neuroscience
|June 2, 2015
PubMed
Summary
This summary is machine-generated.

Altered dopamine levels in dopamine transporter knockout (DAT KO) mice significantly impact licking behavior persistence and pattern generation. These mice exhibit faster learning and extinction of licking behaviors compared to controls.

Keywords:
consummatory behaviordopamine transporter genehyperdopaminergiamousereward

More Related Videos

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

26.7K
Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats
10:44

Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

Published on: August 12, 2015

13.4K

Related Experiment Videos

Last Updated: Apr 11, 2026

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
08:07

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats

Published on: August 24, 2016

9.7K
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

26.7K
Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats
10:44

Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

Published on: August 12, 2015

13.4K

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Genetics

Background:

  • The precise role of dopamine in regulating complex behaviors is not fully elucidated.
  • Dopamine transporter knockout (DAT KO) mice present a valuable model for studying hyperdopaminergic states.

Purpose of the Study:

  • To investigate the influence of elevated dopamine levels on licking behavior patterns.
  • To examine how dopamine affects behavioral persistence and learning during extinction in mice.

Main Methods:

  • Utilized dopamine transporter knockout (DAT KO) mice and wild-type controls.
  • Analyzed licking behavior, including lick rate, lick duration, and inter-lick intervals.
  • Assessed behavioral adjustments during extinction learning.

Main Results:

  • DAT KO mice displayed increased licking bout perseveration, longer individual lick durations, and shorter inter-lick intervals.
  • Both groups showed increased lick pattern variability during extinction, but DAT KO mice adapted more rapidly.
  • DAT KO mice demonstrated quicker extinction of licking behavior.

Conclusions:

  • Dopamine levels significantly modulate the persistence and pattern generation of consummatory behaviors like licking.
  • Elevated dopamine enhances behavioral variability and accelerates learning during extinction in response to environmental feedback changes.
  • Findings highlight dopamine's critical role in behavioral flexibility and habit formation.