Evaluating the effect of aging on interference resolution with time-varying complex networks analysis.
Pedro Ariza1, Elena Solesio-Jofre2, Johann H Martínez3
1Laboratory of Biological Networks, Centre for Biomedical Technology, Technical University of Madrid Madrid, Spain.
Frontiers in Human Neuroscience
|June 2, 2015
Summary
Older adults need more brain synchronization for successful memory recall when facing interference. Key age-related network differences emerge during interference, not just maintenance.
Area of Science:
- Neuroscience
- Cognitive Science
- Network Science
Background:
- Working memory capacity declines with age.
- External interference significantly impacts cognitive tasks.
- Functional brain networks reorganize with age.
Purpose of the Study:
- Investigate age-related changes in functional brain network organization during working memory.
- Examine network dynamics during information maintenance and interference.
- Compare network properties between young and older adults.
Main Methods:
- Graph theory analysis of magnetoencephalography (MEG) data.
- Interference-based working memory task with successful recognition focus.
- Analysis of functional network topology and temporal evolution.
Main Results:
- Older adults exhibit higher cortical synchronization for successful recognition.
- Significant age-group differences in network dynamics appear during interference.
- Network parameter averaging reveals distinct patterns between maintenance and interference.
Conclusions:
- Age-related working memory deficits involve altered functional network synchronization.
- Interference processing is a critical period for observing age-related cognitive differences.
- Functional network reorganization is key to understanding cognitive aging.
Keywords:
aging effectscomplex networks of the brainfunctional networksmagnetoencephalography (MEG)synchronizationMore Related Videos
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