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Two cases of extrapulmonary onset granulomatosis with polyangiitis which caused diffuse alveolar haemorrhage
Halide Kaya1, Sureyya Yilmaz1, Cengizhan Sezgi1
1Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
Abstract:
Granulomatosis with polyangiitis (GPA) is a rare form of vasculitis. Multidisciplinary therapeutic approach and early diagnosis assume vital importance in management of patients with diffuse alveolar haemorrhage caused by GPA, which is a rare complication. The purpose of this study was to present the diagnostic and therapeutic challenges experienced by clinicians in management of two severe cases of GPA with insidious extrapulmonary manifestations which rapidly progressed into acute kidney injury, alveolar haemorrhage and acute respiratory failure.
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