Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

1.3K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.3K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

680
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
680
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

721
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
721
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

688
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
688
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

5.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
5.2K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

4.4K
The pathophysiology of pneumonia involves the following steps:
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rightward Shift of the QRS Axis in Idiopathic Pleuroparenchymal Fibroelastosis.

Open respiratory archives·2026
Same author

Retrograde Stent Graft Placement for Chronic Total Occlusion of the Venous Anastomosis in a Forearm Loop Arteriovenous Graft: A Case Report.

Cureus·2026
Same author

Upper lung asymmetry identifies distinct clinical phenotypes in idiopathic pleuroparenchymal fibroelastosis.

BMC pulmonary medicine·2026
Same author

Japanese Clinical Practice Guidelines for Vascular Tumors, Vascular Malformations, Lymphatic Malformations, and Lymphangiomatosis 2022.

Journal of plastic and reconstructive surgery·2026
Same author

Establishment of DNA methylation during primate germ cell development.

Nature communications·2026
Same author

Japanese clinical practice guidelines for vascular tumors, vascular malformations, lymphatic malformations, and lymphangiomatosis 2022.

Surgery today·2026

Related Experiment Video

Updated: Apr 11, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

526

Diffuse alveolar damage associated with pulmonary thromboembolism.

Yoshiaki Kinoshita1, Atsuhiko Sakamoto1, Takaomi Koga2

  • 1Division of Respiratory Medicine, Department of Internal Medicine, National Hospital Organization, Kokura Medical Center, Fukuoka, Japan.

Respiratory Medicine Case Reports
|June 2, 2015
PubMed
Summary

Pulmonary thromboembolism (PTE) rarely causes lung injury. This case highlights how PTE-induced hypoperfusion may lead to diffuse alveolar damage (DAD) in specific lung regions, challenging existing understanding.

Keywords:
Diffuse alveolar damageHypoperfusionPulmonary artery aneurysmPulmonary thromboembolism

More Related Videos

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
08:02

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

971
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.7K

Related Experiment Videos

Last Updated: Apr 11, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

526
Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
08:02

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

971
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.7K

Area of Science:

  • Pulmonary Medicine
  • Pathology

Background:

  • Pulmonary arterial hypoperfusion typically doesn't cause lung parenchyma ischemia.
  • Pulmonary thromboembolism (PTE) rarely leads to lung injury, except for pulmonary infarction.

Purpose of the Study:

  • To describe a rare case of diffuse alveolar damage (DAD) associated with PTE-induced hypoperfusion.
  • To explore the potential link between PTE and DAD.

Main Methods:

  • Case report of an 86-year-old woman with respiratory failure and bilateral ground-glass opacity.
  • Autopsy findings including pulmonary artery thrombi and localized DAD.

Main Results:

  • Autopsy revealed organized and fresh pulmonary artery thrombi.
  • Localized DAD was identified in bilateral upper lung fields, coinciding with hypoperfused regions due to PTE.

Conclusions:

  • PTE is not typically considered a cause of DAD.
  • This case suggests PTE-induced hypoperfusion may induce DAD in limited circumstances.