Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

743
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
743
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.5K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.5K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

2.3K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.3K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

546
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
546
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

916
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
916
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.5K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening for tuberculosis in prisons: efficacy of a breath-based diagnostic approach in a high prevalence setting.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

Structural and functional characterization of DNAH5 variants in a Portuguese family with primary ciliary dyskinesia.

Journal of assisted reproduction and genetics·2026
Same author

Eradication of Pseudomonas aeruginosa in Non-Cystic Fibrosis Bronchiectasis: A Multicentre Real-World Analysis.

Archivos de bronconeumologia·2026
Same author

Twenty-one years of cutaneous melanoma: stage shift, anatomical patterns and diagnostic trends from a Southern European tertiary center.

Melanoma research·2026
Same author

Cutaneous endometriosis mimicking dermatofibrosarcoma protuberans: a dermoscopic pitfall.

Italian journal of dermatology and venereology·2026
Same author

Effect of anti-tuberculosis drugs on the pharmacokinetics and pharmacodynamics of novel antidiabetic drugs: A scoping review.

Pulmonology·2026

Related Experiment Video

Updated: Apr 11, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.4K

Cerebral tuberculomas - A clinical challenge.

Regina Monteiro1, José Carlos Carneiro1, Claúdia Costa2

  • 1Pulmonology Department, Hospital Center of Vila Nova de Gaia/Espinho (CHVNG/E), Porto, Portugal.

Respiratory Medicine Case Reports
|June 2, 2015
PubMed
Summary

Cerebral tuberculomas, a rare brain tuberculosis form, require prolonged treatment. This case highlights the importance of extended anti-TB drug therapy until complete lesion resolution for effective management.

Keywords:
Cerebral tuberculomasDisseminated tuberculosis

More Related Videos

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

11.4K
Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research
06:25

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Published on: March 29, 2024

1.8K

Related Experiment Videos

Last Updated: Apr 11, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.4K
Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

11.4K
Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research
06:25

Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research

Published on: March 29, 2024

1.8K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Cerebral tuberculomas are rare manifestations of Mycobacterium Tuberculosis (MT) infection.
  • Non-specific symptoms and imaging findings can lead to misdiagnosis, often confused with metastatic disease.
  • Optimal treatment duration for cerebral tuberculomas remains debated.

Purpose of the Study:

  • To present a case of cerebral tuberculoma in an HIV-negative patient.
  • To discuss the diagnostic challenges and treatment approach for cerebral tuberculomas.
  • To emphasize the importance of prolonged anti-tuberculosis therapy.

Main Methods:

  • Case presentation of a 55-year-old male with sudden diplopia.
  • Cerebral computerized tomography (CT) revealed multiple brain lesions with contrast enhancement and edema.
  • Microbiological examination of bronchial wash identified MT sensitive to first-line drugs.

Main Results:

  • The patient received initial 4-drug anti-tuberculosis treatment (HRZE) for 2 months, followed by HR maintenance.
  • Treatment was extended to 24 months due to persistent contrast enhancement in brain lesions at 12 and 18 months.
  • Lesion size decreased, but contrast enhancement indicated potential ongoing inflammation or active disease.

Conclusions:

  • Prolonged anti-tuberculosis treatment is likely prudent for cerebral tuberculomas, even with persistent contrast enhancement.
  • Continuous monitoring and extended therapy may be necessary until complete radiological resolution.
  • This case underscores the complexity of managing cerebral tuberculomas and the need for individualized treatment strategies.