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Updated: Apr 11, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Atypical developmental venous anomaly associated with contrast enhancement and hyperperfusion in the surrounding
Neslin Sahin1, Aynur Solak1, Berhan Genc1
11 Department of Radiology, 2 Department of Neurology, Sifa University School of Medicine, Izmir, Turkey.
Abstract:
Developmental venous anomalies (DVAs) are the most common type of cerebral vascular malformations. They are generally accepted as variants of venous development and frequently identified incidentally, particularly on contrast-enhanced MR imaging. Most of the DVAs do not affect the integrity of the surrounding parenchyma. This article discusses an atypical DVA which is associated with contrast enhancement and increased perfusion within the drainage territory of the DVA, probably due to anomalous venous drainage. These unusual perfusion patterns of the DVAs should be differentiated from other entities such as hypervascular brain tumors or ischemia with hemodynamical changes which have different clinical management.
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