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Updated: Apr 11, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
The neurocognitive profile of the cerebellum in multiple sclerosis
Alessia Sarica1, Antonio Cerasa2, Aldo Quattrone3
1Istituto di Bioimmagini e Fisiologia Molecolare (IBFM), National Research Council (CNR), Catanzaro 88100, Italy. sarica@unicz.it.
Abstract:
In recent years, a high number of studies have demonstrated that neuropsychological functions are altered in multiple sclerosis (MS) patients with cerebellar lesions, mainly including attention, working memory and verbal fluency. Since the present literature is often elusive on this topic, we aim to provide a comprehensive report about the real impact of cerebellar damages (evaluated as volume, lesions or connectivity measures) on cognitive functions. In particular in this review, we report and discuss recent works from 2009 to 2015, which have demonstrated the key role of the cerebellum in cognitive impairment of MS patients.
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