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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
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BOWS (bioinformatics open web services) to centralize bioinformatics tools in web services.
Henrique Velloso1, Ricardo A Vialle2, J Miguel Ortega3
1Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. hvmelo@gmail.com.
BMC Research Notes
|June 3, 2015
Summary
Bioinformatics Open Web Services (BOWS) centralizes tools for easier access. This system allows bioinformaticians to run high-demand applications remotely via web services and HPC clusters.
Area of Science:
- Bioinformatics
- Computational Biology
- Web Services
Background:
- Bioinformaticians encounter challenges with local tool installation and execution.
- A centralized system with an intuitive interface is needed to streamline bioinformatics workflows.
- Web services offer a universal and accessible solution for tool integration.
Purpose of the Study:
- To develop a system for centralized access to bioinformatics tools.
- To enable programmatic access to applications on high-performance computing (HPC) clusters.
- To simplify the execution of complex bioinformatics tasks for researchers.
Main Methods:
- Implementation of Bioinformatics Open Web Services (BOWS) using generic web services.
- Development of front-end and back-end services to intermediate tool access.
- Creation of Java clients for encapsulating web service requests and automatic web page generation.
Main Results:
- BOWS provides programmatic access to registered applications via web services.
- Applications can be installed in any programming language on HPC clusters.
- Users can submit jobs and retrieve results through BOWS front-end services.
Conclusions:
- BOWS enables access to bioinformatics applications from diverse programming languages.
- The system facilitates remote execution of computationally intensive applications on HPC clusters.
- BOWS simplifies the integration and utilization of bioinformatics tools for researchers.
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