Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypertension and Regulation of Blood Pressure

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...

Hypertension II: Pathophysiology

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...

The Cochlea

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

Hypertension I: Introduction

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

Hair Cells

Hair Cells

Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hypertension in autoimmune rheumatic diseases: a position paper from the European Society of Hypertension working group on small arteries. Part A: pathophysiology, prevalence and cardiovascular risk estimation.

Journal of hypertension·2026

Same author

Hypertension in autoimmune rheumatic diseases - a position paper from the European Society of Hypertension working group on small arteries. Part B: Recommendations for the clinical management of hypertension.

Journal of hypertension·2026

Same author

Heat waves and hypertension management in Europe. Do we need 'hot day recommendations'?

Blood pressure·2026

Same author

Developing an AI platform for voice-input medical records in Polish: a digital application for optimisation of physicians' workload.

Scientific reports·2026

Same author

Reperfusion thrombolytic therapy for ischemic stroke in patients on non-vitamin K antagonist oral anticoagulants: study protocol of a phase II randomized clinical trial.

Trials·2026

Same author

The expert position of the Polish Cardiac Society, the Polish Society of Hypertension, and the Polish Society of Nephrology on renal denervation.

Kardiologia polska·2026

Search research articles

Related Experiment Video

Updated: Apr 11, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Hypertension and cochlear hearing loss.

Tomasz Przewoźny¹, Anna Gójska-Grymajło, Mariusz Kwarciany

¹Department of Otolaryngology, Medical University of Gdańsk , Gdańsk , Poland.

|June 3, 2015

Summary

Hypertension significantly contributes to cochlear hearing loss through inner ear damage. Further research is needed to confirm this link in humans due to confounding factors.

Keywords:

Cochlear hearing loss hypertension inner ear diseases

More Related Videos

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

Cochlear Surface Preparation in the Adult Mouse

Cochlear Surface Preparation in the Adult Mouse

Published on: November 6, 2019

Related Experiment Videos

Last Updated: Apr 11, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

Cochlear Surface Preparation in the Adult Mouse

Cochlear Surface Preparation in the Adult Mouse

Published on: November 6, 2019

Area of Science:

Otorhinolaryngology
Cardiology
Physiology

Background:

Hypertension is a major risk factor for cochlear hearing loss.
Pathophysiological processes in the cochlea are linked to hypertension.
Mechanisms include inner ear potassium imbalance and reduced cochlear oxygen.

Purpose of the Study:

To review experimental and clinical research on hypertension's role in cochlear hearing loss.
To explore the pathophysiological mechanisms involved.
To assess the current evidence in humans.

Main Methods:

Review of experimental studies.
Review of clinical research.
Analysis of animal models and human data.

Main Results:

Hypertension impacts cochlear function through mechanisms like potassium recycling disruption and hypoxia.
Human evidence linking hypertension to sensorineural hearing loss is often confounded.
Confounding factors include age, cardiovascular disease, diabetes, obesity, and lifestyle choices.

Conclusions:

Hypertension is a critical factor in cochlear hearing loss.
Further research is necessary to establish a definitive causal link in humans.
Understanding these mechanisms is vital for preventing hearing impairment.