Implications of paraureteral diverticulum for the management of vesicoureteral reflux

Young Jae Im1, Yong Seung Lee1, Sang Woon Kim1

  • 1Department of Pediatric Urology, Severance Children's Hospital, Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.

Insights

Paraureteral diverticulum in children with vesicoureteral reflux is linked to delayed ureteral drainage and increased risk of recurrent urinary tract infections. This finding suggests a need for enhanced monitoring and treatment strategies for affected children.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Radiology

Background:

  • Vesicoureteral reflux (VUR) is a common condition in children.
  • Paraureteral diverticulum is a potential but often overlooked finding in VUR management.
  • The clinical significance of paraureteral diverticulum in VUR remains to be fully elucidated.

Purpose of the Study:

  • To investigate the clinical importance of paraureteral diverticulum in VUR management.
  • To analyze the association between paraureteral diverticulum and recurrent urinary tract infections (UTIs).
  • To evaluate the relationship between paraureteral diverticulum and delayed ureteral drainage.

Main Methods:

  • Retrospective review of 131 children diagnosed with VUR.
  • Diagnosis of VUR and paraureteral diverticulum using voiding cystourethrography.
  • Analysis of delayed ureteral drainage and recurrent UTIs in relation to paraureteral diverticulum.

Main Results:

  • Paraureteral diverticulum was present in 27.2% of refluxing ureters.
  • Ureters with paraureteral diverticulum showed significantly higher rates of delayed ureteral drainage (92.7%).
  • Paraureteral diverticulum was independently associated with delayed ureteral drainage (OR 11.47) and increased risk of recurrent UTIs (P=0.020).

Conclusions:

  • Paraureteral diverticulum in VUR patients increases the risk of recurrent febrile UTIs.
  • These findings highlight the clinical importance of identifying paraureteral diverticulum in VUR.
  • Consideration of more progressive surveillance and treatment protocols for these patients is recommended.
Abstract

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