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Antifungal stewardship in daily practice and health economic implications

Patricia Muñoz1,2,3, Maricela Valerio1,3, Antonio Vena1,2,3

  • 1Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Mycoses
|June 3, 2015
PubMed

Insights

Antifungal stewardship (AFS) programs optimize antifungal use, reducing resistance and costs. This review examines AFS evidence and presents a case study of implementing an AFS program.

Area of Science:

  • Infectious Diseases
  • Antimicrobial Resistance
  • Health Economics

Background:

  • Inappropriate antifungal use drives antifungal resistance and increases healthcare costs.
  • Overuse of antifungals leads to toxicity and economic burden.
  • Antifungal resistance poses a significant global health threat.

Purpose of the Study:

  • To review evidence on Antifungal Stewardship (AFS) programs.
  • To evaluate the health economic impact of AFS.
  • To describe the implementation and challenges of a specific AFS program.

Main Methods:

  • Systematic review of existing literature on AFS programs.
  • Analysis of health economic data related to antifungal use.
  • Retrospective description of a newly implemented AFS program, including steps and difficulties.

Main Results:

  • AFS programs demonstrate positive impacts on antifungal prescribing patterns.
  • Evidence suggests AFS can lead to significant cost savings.
  • Implementation of AFS requires multidisciplinary collaboration and faces specific challenges.

Conclusions:

  • AFS programs are crucial for combating antifungal resistance and improving patient outcomes.
  • Implementing AFS requires careful planning, collaboration, and adaptation to local contexts.
  • Further research is needed to fully elucidate the long-term economic benefits of AFS.
Keywords:
Antifungal stewardshipantifungal therapycandinsempiric antifungalsfluconazoleinvasive candidiasis

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