Related Experiment Video
Updated: Apr 11, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
32.7K
Getting the basics right resolves most cases of uncontrolled and problematic asthma
Eric P de Groot1, Wendy J Kreggemeijer1, Paul L P Brand1,2
1Princess Amalia Children's Centre, Isala Hospital, Zwolle, The Netherlands.
Acta Paediatrica (Oslo, Norway : 1992)
|June 3, 2015
Summary
Most children with uncontrolled asthma have an identifiable cause, such as poor adherence or environmental triggers. True therapy-resistant asthma is rare in pediatric patients, with most cases resolved by addressing basic asthma management issues.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
Background:
- Uncontrolled asthma in children poses a significant clinical challenge.
- The prevalence and causes of true therapy-resistant asthma in pediatric populations are not well-defined.
Purpose of the Study:
- To investigate the underlying causes of uncontrolled asthma in children.
- To determine the prevalence of true therapy-resistant asthma in this cohort.
Main Methods:
- Retrospective chart review of 142 children (aged 5-17) with uncontrolled asthma.
- Patients were referred to a hospital-based pediatric asthma clinic over a five-year period.
Main Results:
- An underlying cause was identified in 97.2% of children.
- Common causes included poor adherence (37.3%), environmental triggers (28.2%), comorbidities (19.7%), incorrect inhaler technique (7.7%), and incorrect diagnosis (4.2%).
- True therapy-resistant asthma was found in only 2.8% of cases; asthma control and lung function normalized after addressing identified issues.
Conclusions:
- Remedial causes in basic asthma management are prevalent in children with uncontrolled asthma.
- True therapy-resistant asthma is rare in children, emphasizing the importance of addressing adherence, triggers, comorbidities, and technique.
Related Concept Videos
01:30Asthma-IV: Nursing Management
4.1K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
4.1K
01:30Asthma-IV: Diagnostic and Management
3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
01:20Asthma: Pathogenesis and Management
1.7K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.7K
01:29Asthma-I: Introduction
3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
01:26Asthma-II: Pathophysiology and Classification
5.0K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
5.0K
01:24Asthma-III: Symptoms and Complications
3.7K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.7K