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Influenza

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Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...

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Enhance airway patency
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Updated: Apr 11, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

[Influenza and pregnancy].

Thomas Gabas¹, Marianne Leruez-Ville², Delphine Le Mercier³

¹Assistance publique-Hôpitaux de Paris, université Paris Descartes Sorbonne Paris Cité, hôpital universitaire Necker-Enfants-Malades, centre d'infectiologie Necker-Pasteur, institut Imagine, service de maladies infectieuses et tropicales, 75015 Paris, France.

Presse Medicale (Paris, France : 1983)

|June 3, 2015

Summary

Pregnant women face higher risks from influenza (flu), both seasonal and pandemic. Vaccination and early antiviral treatment are recommended to protect maternal and fetal health during pregnancy.

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Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

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Published on: April 14, 2011

Area of Science:

Public Health
Infectious Diseases
Obstetrics & Gynecology

Context:

Influenza viruses cause respiratory illness, leading to seasonal epidemics and pandemics.
Pregnant women experience more severe outcomes from seasonal and pandemic influenza, including pneumonia and hospitalization.
Pandemic influenza poses a higher mortality risk to pregnant individuals.

Purpose:

To outline the risks of influenza in pregnant women.
To recommend influenza vaccination and antiviral treatment strategies for pregnant individuals.
To emphasize the need for medical evaluation of flu symptoms during pregnancy.

Summary:

Influenza infection presents significant risks to pregnant women, with increased severity and complications like pneumonia.
Vaccination is advised for all pregnant women during influenza season, regardless of trimester.
Prompt oseltamivir treatment is recommended post-exposure or upon symptom onset, at any stage of pregnancy.

Impact:

Highlights the importance of influenza prevention and management in pregnant populations.
Informs healthcare providers on appropriate vaccination and treatment protocols for pregnant women.
Aims to reduce influenza-related morbidity and mortality in pregnant women and their infants.