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Fentanyl-induced cough is a risk factor for postoperative nausea and vomiting
C C Li1, S S Chen2, C H Huang3
1Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.
British Journal of Anaesthesia
|June 3, 2015
Summary
Fentanyl-induced cough (FIC) during anesthesia increases the risk of postoperative nausea and vomiting (PONV). Patients experiencing FIC were significantly more likely to develop PONV, highlighting FIC as a predictive risk factor.
Area of Science:
- Anesthesiology
- Surgical Patient Outcomes
Background:
- Postoperative nausea and vomiting (PONV) and fentanyl-induced cough (FIC) are common anesthesia-related events.
- Common risk factors may link these two phenomena.
Purpose of the Study:
- To investigate if fentanyl-induced cough (FIC) during anesthesia induction is associated with a higher incidence of postoperative nausea and vomiting (PONV).
Main Methods:
- Prospective cohort study of 502 adult non-smoking gynecological surgical patients.
- Recorded presence of FIC during induction and occurrence of PONV.
- Multivariate analysis to determine the association between FIC and PONV.
Main Results:
- 154 patients (31%) developed FIC.
- The incidence of PONV was significantly higher in the FIC group (56.5%) compared to the non-FIC group (38.2%).
- FIC was identified as a predictive risk factor for PONV (aOR 2.08).
Conclusions:
- Non-smoking women undergoing gynecological surgery who experience FIC during anesthesia induction have an increased incidence of PONV.
- FIC is a significant predictor of PONV in this patient population.
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