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Updated: Apr 11, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Visual Diagnosis: Pinpoint, Nonfollicular, Sterile Pustules on Edematous Erythema in a 15-year-old
Kirishanth Perinpanathan1, Edward Heilman2, Haamid Chamdawala3
1Department of Family Medicine, The Brooklyn Hospital Center, Brooklyn, NY.
Abstract:
AGEP is a rare skin reaction that causes the formation of numerous aseptic pustules on an erythematous base. In most cases, it presents after exposure to drugs, more often antibiotics. Fever and leukocytosis are common. The history, clinical appearance, and histology of the pustules confirm the diagnosis of AGEP. Pustular psoriasis, SJM, and EM must be ruled out. The lesions heal spontaneously within 2 weeks after discontinuation of the offending agent, an occurrence that further supports the diagnosis. Immediate withdrawal of the causative agent and supportive therapy is the mainstay of treatment for AGEP.
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