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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Rheumatoid hand surgery: is there a decline? A 22-year population-based study.

Rajiv Gogna1, Graham Cheung2, Melanie Arundell3

  • 1Department of Trauma and Orthopaedics, University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX UK.

Hand (New York, N.Y.)
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PubMed
Summary
This summary is machine-generated.

The number of hand surgeries for rheumatoid arthritis (RA) patients declined over 22 years. This suggests newer treatments effectively prevent severe joint damage and the need for surgical intervention in RA.

Keywords:
BiologicalDMARDHandRheumatoid arthritisWrist

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Area of Science:

  • Rheumatology
  • Orthopedic Surgery
  • Epidemiology

Background:

  • Rheumatoid arthritis (RA) is a prevalent inflammatory condition affecting approximately 0.8% of the population.
  • RA commonly leads to significant hand and wrist damage, impacting function.
  • Advancements in anti-rheumatic therapies may reduce the incidence of hand deformities in RA patients.

Purpose of the Study:

  • To investigate the trend in hand surgical procedures for RA patients over a 22-year period.
  • To determine if this trend correlates with the introduction of novel anti-rheumatic therapies.

Main Methods:

  • Retrospective, population-based study of RA patients undergoing hand surgery (1990-2012).
  • Procedures included teno-synovectomy, wrist arthrodesis/arthroplasty, and finger arthrodesis.

Main Results:

  • A total of 297 procedures were performed on 153 RA patients.
  • A peak in procedures occurred in 2004, followed by a decline.
  • This decline coincided with earlier and more intensive use of disease-modifying drugs and biological therapies.

Conclusions:

  • A significant decrease in hand surgery procedures for RA patients was observed over 22 years.
  • This trend indicates the success of medical treatments in preventing disease progression and functional decline.