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Methodology of the Pediatric Acute Lung Injury Consensus Conference
Melania M Bembea1, Philippe Jouvet, Douglas Willson
11Department of Anesthesiology and Critical Care, Johns Hopkins University, Baltimore, MD. 2Pediatric Intensive Care Unit, Department of Pediatrics, Sainte-Justine Hospital, Montreal, QC, Canada. 3Division of Pediatric Critical Care, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA. 4Division of Pediatric Critical Care, Penn State Hershey Medical Center, Hershey, PA.
Insights
This article outlines the methodology for the Pediatric Acute Lung Injury Consensus Conference, establishing global expert consensus on pediatric acute respiratory distress syndrome (PARDS) diagnosis and treatment. It highlights key research gaps and future priorities for PARDS management.
Area of Science:
- Pediatric critical care medicine
- Respiratory medicine
- Clinical research methodology
Background:
- Pediatric acute respiratory distress syndrome (PARDS) requires standardized diagnostic and treatment guidelines.
- International collaboration is essential for advancing pediatric critical care research.
Purpose of the Study:
- To describe the methodology employed in the Pediatric Acute Lung Injury Consensus Conference (PALICC).
- To establish a framework for expert consensus on pediatric acute respiratory distress syndrome (PARDS).
Main Methods:
- Utilized the Research ANd Development/University of California, Los Angeles appropriateness method and an expert recommendations process.
- Convened 27 international experts in three meetings over two years, divided into nine subgroups for literature review and consensus building.
Main Results:
- Generated comprehensive recommendations for PARDS management, published across multiple articles.
- Published a methodology article, subtopic articles, and a pathophysiology review in Pediatric Critical Care Medicine.
Conclusions:
- The methodology facilitated global expert input and leveraged modern technology for consensus.
- Recommendations address PARDS management, identify research gaps, and define future research priorities.
Objective:
This article describes the methodology used for the Pediatric Acute Lung Injury Consensus Conference.
Design:
Consensus conference of international experts in pediatric acute respiratory distress syndrome using the Research ANd Development/University of California, Los Angeles appropriateness method and an expert recommendations process developed by the French-speaking intensive care society. Topics related to pediatric acute respiratory distress syndrome were divided into nine subgroups with a review of the literature.
Setting:
A group of 27 experts met three times over the course of 2 years and collaborated in their respective subgroups to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and future research priorities.
Main Results:
The consensus conference resulted in summary of recommendations published in Pediatric Critical Care Medicine, the present Pediatric Acute Lung Injury Consensus Conference methodology article, articles on the nine pediatric acute respiratory distress syndrome subtopics, and a review of pediatric acute respiratory distress syndrome pathophysiology published in this supplement of Pediatric Critical Care Medicine.
Conclusions:
The methodology described involved experts from around the world and the use of modern information technology. This resulted in recommendations for pediatric acute respiratory distress syndrome management, the identification of current research gaps, and future priorities.
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