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Updated: Apr 11, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Gender differences influence overweight smokers' experimentation with electronic nicotine delivery systems
David R Strong1, Mark Myers2, Sarah Linke1
1Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, United States.
Overweight smokers are experimenting more with electronic nicotine delivery systems (ENDS), but this trend did not reduce cigarette use or dependence. Continued monitoring of this high-risk group is essential for public health.
Area of Science:
- Public Health
- Tobacco Control
- Behavioral Science
Background:
- Overweight and obese individuals who use tobacco face elevated risks for cancer, diabetes, heart disease, and chronic tobacco-related conditions.
- Understanding concurrent use of electronic nicotine delivery systems (ENDS) among smokers is crucial for preventing tobacco-related health risks in this comorbid population.
Purpose of the Study:
- To monitor trends in ENDS experimentation among overweight and obese smokers in the US.
- To investigate the association between weight status, gender, and ENDS experimentation.
- To assess if ENDS experimentation impacts cigarette use and dependence in this population.
Main Methods:
- Utilized data from the California Longitudinal Smokers Study (CLSS) cohort established in 2011.
- Surveyed current cigarette smokers at baseline (2011) and follow-up (2012) regarding tobacco use and health behaviors.
- Analyzed trends in ENDS experimentation, particularly among overweight/obese smokers and women.
Main Results:
- Observed a significant increase in reported ENDS experimentation.
- Overweight or obese smokers were more likely to experiment with ENDS, as were women.
- ENDS experimentation was not linked to reduced cigarette use or decreased cigarette dependence.
Conclusions:
- Continued surveillance of this vulnerable population is necessary.
- Further research is needed to understand the health impacts of ENDS experimentation.
- It remains unclear if ENDS facilitate switching to non-combustible tobacco or perpetuate cigarette dependence.
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