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Related Concept Videos

Inhaled Medications01:23

Inhaled Medications

1.1K
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Modified-Release Drug Delivery Systems: Overview01:19

Modified-Release Drug Delivery Systems: Overview

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Modified-release dosage forms are designed to address the limitations of drugs with short biological half-lives. These forms maintain stable therapeutic drug concentrations over extended periods, reducing the need for frequent dosing. A consistent drug level helps minimize peak-trough fluctuations, which can reduce adverse effects, lower the risk of drug resistance, and improve overall treatment effectiveness.One common type of modified-release form is the extended-release (ER) formulation. ER...
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Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Modified-Release Drug Delivery Systems: Influencing Factors01:20

Modified-Release Drug Delivery Systems: Influencing Factors

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Modified-release drug delivery systems are designed to optimize the therapeutic effect of drugs by minimizing side effects, reducing the dosage required, and controlling drug release to align with pharmacokinetic and pharmacodynamic needs. The system depends on two key factors: the drug's release from the formulation and its movement through the body to the target site. Unlike conventional dosage forms, where absorption is the limiting step, the rate of drug release is the key determinant in...
146

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Related Experiment Video

Updated: Apr 11, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Year in Review 2014: Aerosol Delivery Devices.

Timothy R Myers1

  • 1Associate Executive Director of the American Association for Respiratory Care (AARC). myers@aarc.org.

Respiratory Care
|June 4, 2015
PubMed
Summary

Aerosol therapy is crucial for respiratory conditions. Understanding aerosol science and delivery devices, alongside patient education, is vital for effective treatment.

Keywords:
DPIMDIaerosolaerosol maskdelivery devicehigh-flow cannulamechanical ventilationnebulizernoninvasive ventilationpediatricspositive expiratory pressurevalved holding chamber

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Area of Science:

  • Respiratory Medicine
  • Pharmacology
  • Biomedical Engineering

Background:

  • Aerosol therapy is a fundamental treatment for acute and chronic respiratory diseases.
  • Effective aerosol therapy requires understanding the science, device nuances, and patient education.

Purpose of the Study:

  • To review recent literature on aerosol delivery devices.
  • To serve as a key topic resource for healthcare professionals in Respiratory Care.

Main Methods:

  • Literature review of recent studies on aerosol delivery devices.
  • Synthesis of information on device science and patient education.

Main Results:

  • Aerosol therapy combines art and science.
  • Accurate patient education on device use is increasingly important.

Conclusions:

  • Continued advancements in aerosol therapy necessitate a thorough understanding of delivery devices.
  • This review aims to consolidate current knowledge for practical application in respiratory care.