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Mental and Motor Development of Children with Preterm Birth and Children with Fetal Alcohol Syndrome

R Feldmann1, N Girke2

  • 1Pediatrics, University Hospital, Münster, Germany.

Klinische Padiatrie
|June 4, 2015
PubMed

Insights

Children with fetal alcohol syndrome (FAS) experience developmental delays comparable to preterm birth (PTB) with complications. Interestingly, PTB may positively moderate developmental outcomes in FAS by limiting alcohol exposure.

Area of Science:

  • Pediatrics
  • Neurodevelopmental Disorders
  • Public Health

Background:

  • Preterm birth (PTB) is associated with developmental handicaps in children.
  • Fetal alcohol syndrome (FAS) frequently occurs in preterm infants, raising concerns about combined effects on development.

Purpose of the Study:

  • To compare the developmental outcomes of children with PTB and FAS.
  • To investigate the impact of PTB on developmental delays in children with FAS.

Main Methods:

  • The Bayley Scales of Infant Development - Second Edition were used to assess mental (MDI) and psychomotor (PDI) development in 2-year-old children.
  • Participants included PTB children with and without medical complications, and children with FAS, some of whom were also born preterm.

Main Results:

  • Children with PTB and medical complications (PTBc+) and children with FAS exhibited poorer mental and motor development than PTB children without complications (PTBc-).
  • FAS children born preterm demonstrated significantly better mental development than FAS children born at term, with no difference in motor development.

Conclusions:

  • Children with FAS show developmental delays comparable to PTB children with medical complications.
  • PTB does not appear to worsen developmental deficits in FAS; instead, it may offer a protective effect by reducing prenatal alcohol exposure duration.
Abstract

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