Related Experiment Video
Updated: Apr 11, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
The perfect storm: older adults and acute kidney injury
1Christine E Lynn College of Nursing, Florida Atlantic University, Boca Raton, Florida (Dr Hain); and Department of Nephrology & Hypertension, Cleveland Clinic Florida, Weston, Florida (Drs Hain and Paixao).
Abstract:
Older adults have a high risk for acute kidney injury (AKI), often necessitating critical care admission. The majority of older adults live with 1 or more chronic conditions requiring multiple medications, and when faced with acute illness increased vulnerability can lead to poor health outcomes. When combined with circumstances that exacerbate chronic conditions, clinicians may witness the perfect storm. Some factors that contribute to AKI risk include the aging kidney, sepsis, polypharmacy, and nephrotoxic medications and contrast media. This paper discusses specific risks and approaches to care for older adults with AKI who are in critical care.
Related Concept Videos
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury I: Introduction
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury VI: Nursing Management

