Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

5.8K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
5.8K
Exercise Stress Test01:26

Exercise Stress Test

2.1K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
2.1K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

3.1K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
3.1K
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

3.4K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
3.4K
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

1.2K
Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
1.2K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

4.6K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction Note: Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; clinical relevance to peripheral artery disease.

Scientific reports·2026
Same author

Brain-derived neurotrophic factor in human cerebrospinal fluid is elevated after exercise.

Journal of neurophysiology·2026
Same author

Resistance exercise with combined Valsalva manoeuvre acutely increases carotid-femoral pulse wave velocity in healthy untrained individuals.

European journal of applied physiology·2026
Same author

Exercise Increases the Sensitivity of Cerebral Glucose Metabolism to Intranasal Insulin in Young, Healthy Adults.

Journal of neurochemistry·2026
Same author

Cerebral blood flow response to dynamic resistance exercise.

Experimental physiology·2026
Same author

Influence of spontaneous bursts of muscle sympathetic nerve activity on superficial femoral artery and femoral vein flow at rest and during slow deep breathing.

American journal of physiology. Heart and circulatory physiology·2026

Related Experiment Video

Updated: Apr 11, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

22.2K

Postexercise orthostatic intolerance: influence of exercise intensity.

Toby Mündel1, Blake G Perry1, Philip N Ainslie2,3

  • 1School of Sport and Exercise, Massey University, Palmerston North, New Zealand.

Experimental Physiology
|June 5, 2015
PubMed
Summary

More intense exercise accelerates the onset of presyncope (a precursor to fainting) by reducing cardiovascular reserve and causing hypocapnia. This highlights how exercise intensity impacts the body's ability to maintain blood pressure and brain blood flow.

More Related Videos

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.9K
Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.8K

Related Experiment Videos

Last Updated: Apr 11, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

22.2K
Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.9K
Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.8K

Area of Science:

  • Cardiovascular Physiology
  • Exercise Science
  • Autonomic Function

Background:

  • Postexercise hypotension, a drop in blood pressure after exercise, is common and increases syncope risk.
  • The impact of exercise intensity on the development of postexercise hypotension and its relation to syncope onset remains unclear.

Purpose of the Study:

  • To investigate how different exercise intensities affect the time to presyncope after cycling.
  • To determine if exercise intensity influences the physiological mechanisms leading to presyncope.

Main Methods:

  • Healthy participants underwent orthostatic testing to presyncope before and after 1-hour cycling at 30% and 70% of heart rate range.
  • Beat-to-beat middle cerebral artery blood flow velocity (MCAv), mean arterial pressure, and cerebral oxygenation were continuously monitored.

Main Results:

  • Time to presyncope was 32% shorter after high-intensity (70%) exercise compared to low-intensity (30%) exercise.
  • Presyncope occurred at similar physiological thresholds (reduced MCAv, blood pressure, oxygenation, and CO2) regardless of exercise intensity.
  • Post-exercise, MCAv reduction at presyncope was more closely linked to hypocapnia (low CO2) than hypotension.

Conclusions:

  • Higher intensity exercise accelerates presyncope development by reducing cardiovascular reserve and inducing hypocapnia.
  • The physiological triggers for presyncope are consistent, but are reached faster after more intense exercise.
  • These findings suggest that intense exercise may impair the brain's ability to maintain adequate blood flow during orthostatic stress.