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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
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Does previous chemotherapy-induced nausea and vomiting predict postoperative nausea and vomiting?
H B G da Silva1, A M Sousa1, G M N Guimarães1
1Department of Anaesthesia, Cancer Institute of the State of Sao Paulo, Pain Service, São Paulo, Brazil.
Acta Anaesthesiologica Scandinavica
|June 5, 2015
Summary
Previous chemotherapy-induced nausea and vomiting (CINV) is a strong predictor for postoperative nausea and vomiting (PONV) in cancer surgery patients. Incorporating CINV history improves prediction models for PONV risk assessment.
Area of Science:
- Anesthesiology
- Oncology
- Clinical Pharmacology
Background:
- Postoperative nausea and vomiting (PONV) is a common complication following surgery.
- A link between previous PONV and chemotherapy-induced nausea and vomiting (CINV) in oncology patients has been observed.
Purpose of the Study:
- To evaluate if a history of CINV can enhance Apfel's heuristic model for predicting PONV.
- To identify predictors of PONV in cancer surgery patients.
Main Methods:
- Retrospective study of 1500 cancer surgery patients.
- Data collected via electronic medical records, including patient history and PONV occurrence.
- Multiple logistic regression and ROC curve analysis used to assess predictive factors.
Main Results:
- Overall PONV incidence was 26%.
- Apfel's score and previous CINV were significant independent predictors of PONV.
- Previous CINV (OR 3.15) was the most significant addition to Apfel's heuristic.
Conclusions:
- A history of CINV is a potent predictor of PONV in oncology patients.
- CINV history should be considered as an additional risk factor in preoperative PONV assessment for cancer surgery.
- Further prospective studies are recommended to validate CINV as a PONV risk factor.
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