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Updated: Apr 11, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
[Dysbiosis and its consequences on oral cavity in children and adolescents]
T Suladze1, T Shishniashvili1, V Margvelashvili1
1Tbilisi State Medical University; Iv. Javakhishvili Tbilisi State University, Georgia.
Abstract:
Gastrointestinal tract (GIT) diseases in children are often accompanied by changes in oral cavity, which is caused by common function of GIT and oral cavity organs. During last years, the number of dysbiosis of various severities has dramatically increased, which directly affects the oral cavity - dental hard tissue mineralization, especially in children and adolescents. The aim of our study was to identify the frequency of dysbiosis in children and adolescents and its influence on dental and general health. 279 patients aged 1 - 17 years were examined. Examinations have shown, that in patients with I-II degree dysbiosis spread and intensity (DMF index) of dental caries is significantly lower - 58,2% and 2,7 intensity, compared to III-IV degree dysbiosis, where 71,8% have caries with 4,2 intensity. According to this, dental and general health status in children and adolescents is highly dependent on severity of GI tract pathologies, particularly on qualitative and/or quantitative content of microbyotes of GI tract.
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