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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Positron Emission Tomography01:29

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Apr 11, 2026

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models
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PET Imaging in Sarcoma.

Stephen Becher1, Shervin Oskouei1

  • 1Department of Orthopedic Surgery, Emory University, 57 Executive Park South, 160-3, Atlanta, GA 30329, USA.

The Orthopedic Clinics of North America
|June 5, 2015
PubMed
Summary
This summary is machine-generated.

Positron Emission Tomography (PET) imaging is not recommended as a routine test for sarcoma patients. Current evidence lacks cost-benefit analysis and clear advantages over conventional imaging, requiring further study for specific applications.

Keywords:
ExtremityPETPET/CTSarcomaSoft tissue

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Area of Science:

  • Oncology
  • Radiology
  • Nuclear Medicine

Background:

  • Positron Emission Tomography (PET) imaging has been explored for various applications in sarcoma management.
  • These include biopsy guidance, therapeutic monitoring, tumor detection, grading, staging, and prognostication.

Purpose of the Study:

  • To evaluate the current evidence on the utility of PET imaging in sarcoma diagnosis and treatment.
  • To determine if PET/computed tomography (CT) offers significant added benefits over conventional imaging methods.

Main Methods:

  • Review of existing studies and evidence regarding PET imaging in sarcoma.
  • Analysis of cost-benefit, diagnostic accuracy, and impact on clinical decision-making.

Main Results:

  • Current evidence does not support PET/CT as a routine test for sarcoma.
  • Lack of cost-benefit analysis and demonstrated added value over conventional imaging for most applications.
  • Potential utility in specific subtypes or neoadjuvant chemotherapy monitoring requires further investigation.

Conclusions:

  • PET/CT cannot be routinely recommended for sarcoma patients at this time.
  • Further research is needed to establish its role in specific clinical scenarios and patient populations before it becomes standard of care.