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Chemotherapy-associated anemia in patients with lung cancer: an epidemiological, retrospective and multicenter study
Jose Muñoz-Langa1, Javier De Castro2, Pere Gascó3
11Hospital Doctor Peset, Valencia, Spain.
Aim:
Providing epidemiological data and treatment of anemia in lung cancer patients undergoing first-line chemotherapy.
Methods:
Epidemiological, observational, retrospective and multicenter study carried out at 30 sites throughout Spain.
Results:
The prevalence of anemia (hemoglobin [Hb] level <12 g/dl) was 18.3% and the incidence 80.7%. Mean Hb levels were 13.4 g/dl (95% Cl: 13.2-13.6) and 11.5 g/dl (95% Cl: 11.3-11.7) at starting and at the end of chemotherapy, respectively. Of the 294 patients with anemia, 174 (59.2%) were treated. Erythropoiesis-stimulating agents were given to 90.2% patients, alone in 31.6% and combined iron in 39.7%, transfusion in 9.2% and iron and transfusion in 9.8%.
Conclusion:
These results suggest an appropriate and rational use of erythropoiesis-stimulating agents in the treatment of chemotherapy-associated anemia in lung cancer patients. [corrected].