Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pigmentation01:19

Pigmentation

5.0K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
5.0K
Papillary Dermis01:11

Papillary Dermis

6.9K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.9K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.2K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.2K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

4.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
4.2K
Skin Cancer01:30

Skin Cancer

6.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.6K
Acne Infection01:27

Acne Infection

64
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
64

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Survival and Health-Related Quality of Life after Hospitalization for Necrotizing Soft Tissue Infections of the Upper Extremity: A Long-Term Outcome Study.

Journal of hand and microsurgery·2022
Same author

The Die Punch Fragment: Analysis of Fragment Geometry and Need for Fixation.

Journal of hand and microsurgery·2022
Same author

Hyperbaric oxygen treatment for mastectomy flap ischaemia: A case series of 50 breasts.

Diving and hyperbaric medicine·2021
Same author

Predictors of Secondary Ulnar Shortening and Reoperation After Arthroscopic TFCC Debridement.

Hand (New York, N.Y.)·2021
Same author

An Economic Analysis of Direct Costs of Distal Radius Fixation and the Implications of a Disposable Distal Radius Kit.

Journal of orthopaedic trauma·2021
Same author

Carpometacarpal 4/5 Fracture Dislocations: Fracture Morphology and Surgical Treatment.

Journal of hand and microsurgery·2020

Related Experiment Video

Updated: Apr 11, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

899

[A man with multiple erythematous and hyperpigmented papules].

Svenna H W L Verhiel1, Lisette T Hoekstra

  • 1Maastricht UMC+, afd. Plastische Chirurgie, Maastricht.

Nederlands Tijdschrift Voor Geneeskunde
|June 5, 2015
PubMed
Summary

A Syrian war patient developed keloids after metal particle injury. Treatment involved intralesional glucocorticoid injections and pressure therapy for this fibroproliferative scarring.

Area of Science:

  • Dermatology
  • Wound Healing
  • Pathology

Background:

  • Keloids are benign fibroproliferative tumors resulting from abnormal wound healing.
  • They represent an overproduction of extracellular matrix, leading to excessive scar tissue formation.
  • Trauma, including penetrating injuries, is a known trigger for keloid development.

Observation:

  • A 25-year-old male presented with multiple polycyclic papules.
  • The patient reported a history of bombardment exposure and direct injury from metal particles.
  • The lesions were clinically identified as keloids.

Findings:

  • The patient's condition was diagnosed as keloid formation secondary to penetrating trauma from metal fragments.
  • Histopathological examination would confirm the characteristic features of fibroproliferative scarring.

More Related Videos

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
04:43

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

1.0K
Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.8K

Related Experiment Videos

Last Updated: Apr 11, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

899
Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
04:43

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

1.0K
Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.8K
  • The observed lesions represent a significant cutaneous response to injury.

    • Implications:

    • This case highlights the potential for keloid development following combat-related injuries involving penetrating foreign bodies.
    • Effective management strategies for keloids, such as intralesional glucocorticoid injections and pressure therapy, were employed.
    • Understanding the etiology and treatment of keloids in diverse traumatic settings is crucial for dermatological practice.