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Systematic review: Body composition in children with inflammatory bowel disease
D Thangarajah1, M J Hyde1, V K S Konteti1
1Section of Neonatal Medicine, Department of Medicine, Imperial College London, UK.
Alimentary Pharmacology & Therapeutics
|June 6, 2015
Summary
Children with inflammatory bowel disease (IBD) often experience reduced lean body mass. Body fat changes in pediatric IBD patients require further investigation for a comprehensive understanding of their health.
Area of Science:
- Pediatric Gastroenterology
- Nutritional Science
- Body Composition Analysis
Background:
- Pediatric inflammatory bowel disease (IBD) is linked to malnutrition, weight loss, and growth issues.
- While bone deficits are documented, other body composition changes in children with IBD are poorly understood.
Purpose of the Study:
- To identify alterations in non-bone tissues within pediatric IBD patients.
- To explore how demographic and disease factors influence these body composition changes.
Main Methods:
- A systematic review of studies comparing body composition in children (<17 years) with IBD to control groups.
- Searched PubMed and Web of Science databases in May 2014.
Main Results:
- 21 studies involving 1479 children with IBD (Crohn's disease and ulcerative colitis) were analyzed.
- Lean mass deficits were prevalent, affecting 93.6% of Crohn's disease and 47.7% of ulcerative colitis patients.
- Body fat alterations were inconsistent and require further definition.
Conclusions:
- Reduced lean mass is a significant issue in most children with Crohn's disease and half with ulcerative colitis.
- Further research is essential to define body fat changes and their distribution in pediatric IBD.
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