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Occurrence of the Codon 24 (A > T) Mutation in the Mauritanian Population
Fatimetou Veten1, Sidi Ghaber, Nordine Habti
1Unité de Recherche sur les Biomarqueurs de la Population Mauritanienne, Faculté des Sciences et Techniques, Université des Sciences de Technologies et de Médicine , Nouakchott , Mauritanie.
Abstract:
Using direct DNA sequencing, we identified the codon 24 (A > T) (HBB: c.72T > A, p.Gly24Gly), mutation in two out of 15 Mauritanian β-thalassemia (β-thal) carriers. Both were of Black origin and had hematological indices compatible with mild β-thal minor. Could this variant be more common than expected in the Black Mauritanian population?
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