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Updated: Apr 11, 2026

Spectral Confocal Imaging of Fluorescently tagged Nicotinic Receptors in Knock-in Mice with Chronic Nicotine Administration
Published on: February 10, 2012
Three Decades of High-Dose Nicotine Gum Dependence Treated With Nicotine Patches
1The Sydney Clinic, Bronte, Australia mendel@bigpond.net.au.
Introduction:
Some long-term nicotine gum users are addicted to nicotine and may need assistance to stop. There is no published evidence on the use of nicotine patches for this purpose.
Case Description:
A 45-year old man presented with a 30-year history of high-dose nicotine gum use (up to 200mg nicotine per day). He was highly nicotine dependent and had failed repeatedly to stop using nicotine gum use in the past. Within a week of commencing nicotine patches he was able to cease nicotine gum with minimal discomfort and has remained nicotine-free for 6 months, with abstinence confirmed biochemically. His severe sweating disorder rapidly resolved with cessation of the gum.
Conclusion:
Nicotine patches may be an effective treatment for long-term nicotine gum addiction.
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