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Pharmacoeconomic evaluation of hospitalised pre-dialysis and dialysis patients: A comparative study

Uday Venkat Mateti1, Anantha Naik Nagappa1, Santosha Vooradi1

  • 1Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India.

The Australasian Medical Journal
|June 6, 2015
PubMed

Insights

Hospitalized patients with chronic kidney disease (CKD) incur higher direct medical costs when undergoing dialysis compared to pre-dialysis. Factors like medication number and hospital stay duration significantly impact total costs for CKD patients.

Area of Science:

  • Nephrology
  • Health Economics
  • Pharmacoeconomics

Background:

  • Chronic kidney disease (CKD) progression is influenced by factors like limited access to medical services, delayed referrals, and financial constraints.
  • Understanding the economic burden of CKD is crucial for effective patient management and healthcare resource allocation.

Purpose of the Study:

  • To compare pharmacoeconomic-related direct medical and non-medical costs between hospitalized pre-dialysis and dialysis patients.
  • To identify key factors influencing total direct costs in CKD patients.

Main Methods:

  • A prospective observational study involving 100 inpatients in a Nephrology department.
  • Patients were categorized into pre-dialysis and dialysis groups based on their treatment status.
  • Data on direct medical and non-medical costs were collected from patient records and bills.

Main Results:

  • Dialysis patients incurred significantly higher median direct medical costs (USD $76.47) compared to pre-dialysis patients (USD $29.43).
  • Median direct non-medical costs showed no significant difference between the pre-dialysis (USD $8.88) and dialysis (USD $7.75) groups.
  • Total direct costs differed significantly between the two patient groups.

Conclusions:

  • Significant differences exist in direct total costs between pre-dialysis and dialysis patients.
  • The number of medications prescribed and the length of hospital stay are identified as significant determinants of direct total costs in CKD patients.
Abstract

Keywords:
Chronic kidney diseasecostdialysiseconomicshospitalisation

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